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ABCG2 TRANSPORTER
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DeCS
Descriptor
English
:
ATP Binding Cassette Transporter, Sub-Family G, Member 2
Descriptor
Spanish
:
Transportador de Casetes de Unión a ATP, Subfamilia G, Miembro 2
Descriptor
Portuguese
:
Membro 2 da Subfamília G de Transportadores de Cassetes de Ligação de ATP
Synonyms
English
:
ABCG2 Protein
ABCG2 Transporter
CD338 Antigen
Antigen, CD338
Tree Number:
D12.776.157.530.100.228.500
D12.776.395.550.020.457.500
D12.776.543.550.192.457.500
D12.776.543.585.100.228.500
D23.050.301.264.035.272
D23.101.100.110.272
Definition
English
:
An ATP binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of
STEROLS
, and in the
absorption
and efflux of many drugs. Its efflux activity for
ANTINEOPLASTIC AGENTS
contributes to
DRUG RESISTANCE
. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by
NEOPLASTIC STEM CELLS.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56579
Unique Identifier:
D000070997
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS